Published: 28 Feb 2025

Advances in Microfluidic Bioprinting for Multi-Material Multi-Cellular Tissue Constructs

Volume 1

3D bioprinting enables fabrication of cell-laden bioinks into complex, biomimetic tissues. However, achieving the spatial and functional heterogeneity of native tissues still poses significant challenges. Microfluidics has emerged as a complementary technology, offering precise control over material flow, mixing, and deposition at the microscale. This review highlights the integration of microfluidics with 3D bioprinting, with a particular focus on the development of advanced “printhead-on-a-chip” systems that enable real-time material switching,..