Published: 09 Jan 2025
How Caffeine Affects Alpha-Amylase: An In Vivo Study
Volume 2
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Farnaz Banakar
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Raheleh Kheirbakhsh
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Elnaz Mahrampour
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Azadeh Ebrahim-Habibi
aehabibi@sina.tums.ac.ir,azadehabibi@yahoo.fr
Background: Caffeine is a widely consumed psychostimulant with various effects, including weight and metabolic parameters. Caffeine consumption has been associated with increased blood glucose levels and reduced insulin sensitivity. Since xanthine derivatives like caffeine can activate alpha-amylase, an enzyme essential for carbohydrate-to-glucose conversion, this study investigates whether this translates to increased amylase activity in living organisms and explores potential gene expression changes. Methods: Male NMRI mice were divided to 5..