Published: 21 Mar 2025
Characteristics of Tumor Infiltrating Lymphocytes in Patients with Benign and Malignant Sinonasal Neoplasms
Volume 1
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Darya Nizheharodava
nzh@tut.by -
Elizaveta Nazaranka
el.m.nazarenko@gmail.com -
Natallia Marozava
natalim-22@yandex.ru -
Galina Ivanchyk
immunology.by@gmail.com -
Volha Karnialiuk
olsol70@mail.ru -
Zhanna Kaliadzich
janept@list.ru -
Marina Zafranskaya
zafranskaya@gmail.com
Introduction. Tumor infiltrating lymphocytes are a major component of sinonasal neoplasms, actively populating tumor tissue, yet their role remains poorly understood. The aim is to characterize subsets and functional profiles of tumor infiltrating lymphocytes in patients with benign and malignant sinonasal tumors. Materials and methods. Tumor infiltrating lymphocytes were isolated from the biopsy material of 58 patients: 18 with sinonasal malignancies, 23 with inverted papilloma and 17 with polypous rhinosinusitis..