Available Online: 25 Dec 2025
Origin, Evolution, and Regulation of Cancer Genes: An Overview
Volume 2
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Mulkh Raj Ahuja
mrahuja@hotmail.com
Cancer is a disease of living cells in the multicellular organisms. Its origins are closely associated with the evolution of multicellularity, which emerged billions of years ago. The “incipient cancer genes” (proto-oncogenes) presumably evolved from cell reproduction genes during the evolutionary transition from unicellular to multicellular organisms. Although initially these incipient cancer genes were involved in rapid cell division required for growth at specific developmental stages, their activity had to..
