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Biomaterials Connect

Volume 3


open-access Research Article

Available Online: 24 Jul 2026

Long-Term Clinical Outcomes of the Use of Endo-Sealants in the Treatment of Teeth with Destructive Forms of Apical Periodontitis

Volume 3

Radiographic examination remains the primary method used to assess endodontic treatment quality, and the search for objective evaluation methods remains relevant, as standardized criteria would let clinicians evaluate their own work objectively. Objective: To evaluate the effectiveness of treating teeth with periapical pathology based on the state of apical constriction, using clinical and radiographic examination to substantiate the choice of obturation material. Methods: The study involved 156 participants with 194..

open-access Review Article

Available Online: 14 Jul 2026

Importance of Cell Alignment in Cardiac Tissue Engineering

Volume 3

Native myocardium is a structurally anisotropic, electromechanically integrated tissue in which cardiomyocytes, extracellular matrix fibers, vascular structures, and conduction pathways are organized across multiple length scales. Rather than a simple stack of discrete layers with slight misalignment, its defining architectural feature is a continuous transmural gradient in predominant myofiber angle from the endocardial to the epicardial surface—an organization that underlies anisotropic electrical propagation, regional deformation, ventricular torsion, wall thickening, and..

open-access Review Article

Available Online: 01 Jul 2026

Clinical Effectiveness of Resin Modified Calcium Silicate Cements

Volume 3

This review provides a thorough and critical analysis of the basic properties of resin-modified calcium silicate cements, focusing on issues related to their cytotoxicity and mineralization potential. An important question that remains unresolved in the dental literature. The aim of this review is to examine the available literature on the long-term clinical efficacy of resin-modified calcium silicate cements for direct pulp capping. A literature search was conducted using three electronic..

open-access Research Article

Published: 03 Jun 2026

Age and Charge Effects in Cortical Bone: Raman Study of Phosphate Ions Stretching

Volume 3

A quantitative assessment of internal electrostatic fields in bone tissue was conducted within the framework of the “bone-battery” concept. The influence of these fields on atomic structure and dynamics may have been significantly underestimated. To test this hypothesis, Raman spectroscopy was applied to cortical bone samples from young and mature rats. Particular attention was given to the v1(PO43−) band at 960 cm−1 in the Raman spectra to investigate the coupling..

open-access Review Article

Published: 20 May 2026

Digital Twin Applications in Biomaterials Science: Toward Predictive Design and Personalized Healthcare

Volume 3