Cancer Research and Therapy Connect is a peer-reviewed, open-access journal dedicated to advancing the full spectrum of cancer research, from fundamental biology to therapeutic innovation. The journal publishes innovative research that deepens understanding of the molecular, cellular, and immunological mechanisms driving cancer initiation, progression, and treatment response. Our goal is to accelerate the translation of scientific discoveries into effective, patient-centered cancer care.
The journal’s scope covers the following areas:
- Cancer Biology and Mechanisms – Oncogenesis, tumor suppressor biology, signaling pathways, tumor microenvironment, metastasis, and the discovery and validation of novel therapeutic targets.
- Therapeutics and Drug Development – Small-molecule inhibitors, monoclonal antibodies, antibody–drug conjugates (ADCs), peptide- and protein-based drugs, next-generation modalities such as PROTACs, chemotherapy, radiotherapy, and other emerging treatment approaches.
- Immunotherapy and Precision Oncology – Immune checkpoint inhibitors, bispecific antibodies, CAR-T and TCR-based therapies, cancer vaccines, and biomarker-guided treatment strategies.
- Drug Resistance and Combination Therapy – Mechanisms of resistance and rational combination regimens integrating targeted, cytotoxic, and immune-based agents.
- Clinical and Translational Research – Clinical trials across all therapeutic modalities, pharmacogenomics, predictive and prognostic biomarkers and diagnostics — including screening biomarkers, liquid biopsy, molecular diagnostics, imaging technologies, and early detection approaches supporting timely clinical intervention.
- Technological and Methodological Advances – CRISPR and gene-editing tools, single-cell omics, proteomics, nanomedicine, and computational or AI-driven approaches for target discovery, diagnostics, and drug development.
Cancer Research and Therapy Connect aims to serve as a platform for researchers, clinicians, and industry experts to share insights, foster collaboration, and explore emerging directions across the cancer research and therapy landscape - from basic discovery to clinical application.